{ "@context": "http://iiif.io/api/presentation/3/context.json", "id": "https://budc.barry.edu/iiif/manifest/AA00001569/00001", "type": "Manifest", "label": { "none": [ "Lack of glycosylation does not affect the antigenicity of epithelial mucin 1 in a rare case of aglyconic extramammary Paget\u0027s disease" ] }, "metadata": [ { "label": { "en": [ "Abstract" ] }, "value": { ",": [ "It has been noted in the research literature that there is no systematic difference in affinity of monoclonal antibodies raised against the native glycoprotein (MabW) as compared to monoclonal antibodies raised against the aglyconic tandem polypeptide of the core protein (MabT) for the native glycosylated epithelial mucin 1. However, there is no research in the literature comparing the affinity of these two monoclonal antibodies for the aglyconic epithelial mucin 1 core protein. This project investigated the affinity of MabW and MabT for the aglyconic epithelial mucin 1 core protein in an atypical case of extramammary Paget\u2019s disease. The limiting dilution was used and results were analyzed using the Kolmogorov- Smirnov two sample test with an alpha of 0.05. There was no systematic difference in the affinity for the aglyconic epithelial mucin 1 between MabW and MabT. This suggests that the numerous oligosaccharide side chains of the human epithelial mucin 1 have little to do with antigenicity." ], "none": [ "Extramammary Paget\u0027s Disease (EMPD). Adenocarcinoma. Neoplastic cells." ] } }, { "label": { "en": [ "Classification" ] }, "value": { "none": [ "QM491.H46 2008" ] } }, { "label": { "en": [ "Publication Date" ] }, "value": { "none": [ "2008" ] } }, { "label": { "en": [ "Genre" ] }, "value": { "none": [ "Academic theses" ] } }, { "label": { "en": [ "Holding Location" ] }, "value": { "none": [ "Barry University Archives and Special Collections" ] } }, { "label": { "en": [ "Resource Identifier" ] }, "value": { "none": [ "QM491.H46 2008_HendersonShakira" ] } }, { "label": { "en": [ "Language" ] }, "value": { "none": [ "English" ] } }, { "label": { "en": [ "Permanent Link" ] }, "value": { "none": [ "http://sobekcmsrv.barrynet.barry.edu/AA00001569/00001" ] } }, { "label": { "en": [ "Creator" ] }, "value": { "none": [ "Henderson, Shakira Lita Ismay" ] } }, { "label": { "en": [ "Note" ] }, "value": { "none": [ "Thesis (M.S.)--Barry University, 2008.", "Includes bibliographical references (leaves 49-56)." ] } }, { "label": { "en": [ "Physical Description" ] }, "value": { "none": [ "v, 56 leaves : ill., 7 leaves of plates ; 28 cm" ] } }, { "label": { "en": [ "Publisher" ] }, "value": { "none": [ "Barry University" ] } }, { "label": { "en": [ "Place of Publication" ] }, "value": { "none": [ "Miami, Fla." ] } }, { "label": { "en": [ "Type" ] }, "value": { "none": [ "Book" ] } }, { "label": { "en": [ "Rights Management" ] }, "value": { "none": [ "Copyright Shakira L. I. Henderson. Permission granted to Barry University to digitize, archive and distribute this item for non-profit research and educational purposes. Any reuse of this item in excess of fair use or other copyright exemptions requires permission of the copyright holder." ] } }, { "label": { "en": [ "Source Institution" ] }, "value": { "none": [ "Barry University" ] } }, { "label": { "en": [ "Subjects / Keywords" ] }, "value": { "none": [ "Apocrine glands", "Breast neoplasms", "Mammary glands" ] } }, { "label": { "en": [ "Degree Disciplines" ] }, "value": { "none": [ "Medical sciences" ] } }, { "label": { "en": [ "Title" ] }, "value": { "none": [ "Lack of glycosylation does not affect the antigenicity of epithelial mucin 1 in a rare case of aglyconic extramammary Paget\u0027s disease" ] } }, { "label": { "en": [ "Series Title" ] }, "value": { "none": [ "Barry University Theses -- School of Graduate Medical -- Anatomy" ] } }, { "label": { "en": [ "Format" ] }, "value": { "none": [ "Book" ] } }, { "label": { "en": [ "Digital Resource Creation Date" ] }, "value": { "none": [ "4/22/2020" ] } } ], "service": [ { "@context": "http://iiif.io/api/search/2/context.json", "id": "https://budc.barry.edu/iiif/manifest/AA00001569/00001/search", "type": "SearchService2", "profile": "http://iiif.io/api/search/2/search" } ], "seeAlso": [ { "id": "https://budc.barry.edu/content/AA/00/00/15/69/00001/AA00001569_00001.mets.xml", "type": "Dataset", "format": "application/mets\u002Bxml", "label": { "en": "METS" } }, { "id": "https://budc.barry.edu/content/AA/00/00/15/69/00001/marc.xml", "type": "Dataset", "format": "application/marcxml\u002Bxml", "label": { "en": "MARCXML" } } ], "items": [] }